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1

Development of Improved Double-Nanobody Sandwich ELISAs for Human Soluble Epoxide Hydrolase Detection in Peripheral Blood Mononuclear Cells of Diabetic Patients and the Prefrontal Cortex of Multiple Sclerosis Patients

Li, Dongyang, Morisseau, Christophe, McReynolds, Cindy B., Duflot, Thomas, Bellien, JÃ©rÃ©my, Nagra, Rashed M., Taha, Ameer Y., Hammock, Bruce D.

Journal:

Analytical Chemistry

Year:

2020

File:

PDF, 891 KB

2020

2

Synthesis and Structure−Activity Relationship Studies of Urea-Containing Pyrazoles as Dual Inhibitors of Cyclooxygenase-2 and Soluble Epoxide Hydrolase

Hwang, Sung Hee, Wagner, Karen M., Morisseau, Christophe, Liu, Jun-Yan, Dong, Hua, Wecksler, Aaron T., Hammock, Bruce D.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.39 MB

english, 2011

3

EPOXIDE HYDROLASES: Mechanisms, Inhibitor Designs, and Biological Roles

Morisseau, Christophe, Hammock, Bruce D.

Journal:

Annual Review of Pharmacology

Year:

2005

Language:

english

File:

PDF, 467 KB

english, 2005

4

Structural refinement of inhibitors of urea-based soluble epoxide hydrolases

Christophe Morisseau, Marvin H. Goodrow, John W. Newman, Craig E. Wheelock, Deanna L. Dowdy, Bruce D. Hammock

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 240 KB

english, 2002

5

Impact of Soluble Epoxide Hydrolase and Epoxyeicosanoids on Human Health

Morisseau, Christophe, Hammock, Bruce D.

Journal:

Annual Review of Pharmacology

Year:

2013

Language:

english

File:

PDF, 728 KB

english, 2013

6

Isolation of a strain of Agrobacterium tumefaciens ( Rhizobium radiobacter ) utilizing methylene urea (ureaformaldehyde) as nitrogen source

Koivunen, Marja E, Morisseau, Christophe, Horwath, William R, Hammock, Bruce D

Journal:

Canadian Journal of Microbiology

Year:

2004

File:

PDF, 191 KB

2004

7

Pharmacological Inhibition of Soluble Epoxide Hydrolase Ameliorates Diet-Induced Metabolic Syndrome in Rats

Iyer, Abishek, Kauter, Kathleen, Alam, Md. Ashraful, Hwang, Sung Hee, Morisseau, Christophe, Hammock, Bruce D., Brown, Lindsay

Journal:

Experimental Diabetes Research

Year:

2012

Language:

english

File:

PDF, 3.13 MB

english, 2012

8

Correction to Optimized Inhibitors of Soluble Epoxide Hydrolase Improve in Vitro Target Residence Time and in Vivo Efficacy

Lee, Kin Sing Stephen, Liu, Jun-Yan, Wagner, Karen M., Pakhomova, Svetlana, Dong, Hua, Morisseau, Christophe, Fu, Samuel H., Yang, Jun, Wang, Peng, Ulu, Arzu, Mate, Christina A., Nguyen, Long V., Hwan

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 396 KB

english, 2018

9

Dimethyl Sulfoxide Decreases Levels of Oxylipin Diols in Mouse Liver

Deol, Poonamjot, Yang, Jun, Morisseau, Christophe, Hammock, Bruce D., Sladek, Frances M.

Journal:

Frontiers in Pharmacology

Year:

2019

Language:

english

File:

PDF, 996 KB

english, 2019

10

Enantioselective hydrolysis of p-nitrostyrene oxide by an epoxide hydrolase preparation from Aspergillus niger

Hariharan Nellaiah, Christophe Morisseau, Alain Archelas, Roland Furstoss, Jacques C. Baratti

Journal:

Biotechnology and Bioengineering

Year:

1996

Language:

english

File:

PDF, 809 KB

english, 1996

11

Epoxide Hydrolases: Mechanisms, Inhibitor Designs, and Biological Roles

Christophe Morisseau, Bruce D. Hammock

Journal:

Year:

2005

File:

PDF, 8 KB

2005

12

Differential subcellular distribution and colocalization of the microsomal and soluble epoxide hydrolases in cultured neonatal rat brain cortical astrocytes

Seema Rawal, Christophe Morisseau, Bruce D. Hammock, Amruthesh C. Shivachar

Journal:

Journal of Neuroscience Research

Year:

2009

Language:

english

File:

PDF, 341 KB

english, 2009

13

Design of bioavailable derivatives of 12-(3-adamantan-1-yl-ureido)dodecanoic acid, a potent inhibitor of the soluble epoxide hydrolase

In-Hae Kim, Kosuke Nishi, Hsing-Ju Tsai, Tanya Bradford, Yasuko Koda, Takaho Watanabe, Christophe Morisseau, Joanne Blanchfield, Istvan Toth, Bruce D. Hammock

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 230 KB

english, 2007

14

Solid-phase combinatorial approach for the optimization of soluble epoxide hydrolase inhibitors

Sung Hee Hwang, Christophe Morisseau, Zung Do, Bruce D. Hammock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 159 KB

english, 2006

15

Fluorescent substrates for soluble epoxide hydrolase and application to inhibition studies

Paul D. Jones, Nicola M. Wolf, Christophe Morisseau, Paul Whetstone, Bertold Hock, Bruce D. Hammock

Journal:

Analytical Biochemistry

Year:

2005

Language:

english

File:

PDF, 249 KB

english, 2005

16

Development of a high-throughput screen for soluble epoxide hydrolase inhibition

Nicola M. Wolf, Christophe Morisseau, Paul D. Jones, Bertold Hock, Bruce D. Hammock

Journal:

Analytical Biochemistry

Year:

2006

Language:

english

File:

PDF, 344 KB

english, 2006

17

Novel and highly sensitive fluorescent assay for leucine aminopeptidases

Huazhang Huang, Hiromasa Tanaka, Bruce D. Hammock, Christophe Morisseau

Journal:

Analytical Biochemistry

Year:

2009

Language:

english

File:

PDF, 578 KB

english, 2009

18

Development of fluorescent substrates for microsomal epoxide hydrolase and application to inhibition studies

Christophe Morisseau, Maud Bernay, Aurélie Escaich, James R. Sanborn, Jozsef Lango, Bruce D. Hammock

Journal:

Analytical Biochemistry

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

19

High-throughput pharmacokinetic method: Cassette dosing in mice associated with minuscule serial bleedings and LC/MS/MS analysis

Takaho Watanabe, Daniela Schulz, Christophe Morisseau, Bruce D. Hammock

Journal:

Analytica Chimica Acta

Year:

2006

Language:

english

File:

PDF, 307 KB

english, 2006

20

The 5-substituted piperazine as a novel secondary pharmacophore greatly improving the physical properties of urea-based inhibitors of soluble epoxide hydrolase

Hui-Yuan Li, Yi Jin, Christophe Morisseau, Bruce D. Hammock, Ya-Qiu Long

Journal:

Bioorganic & Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 168 KB

english, 2006

21

Peptidyl-urea based inhibitors of soluble epoxide hydrolases

Christophe Morisseau, John W. Newman, Hsing-Ju Tsai, Preston A. Baecker, Bruce D. Hammock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 207 KB

english, 2006

22

Salicylate–urea-based soluble epoxide hydrolase inhibitors with high metabolic and chemical stabilities

Takeo Kasagami, In-Hae Kim, Hsing-Ju Tsai, Kosuke Nishi, Bruce D. Hammock, Christophe Morisseau

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 1.28 MB

english, 2009

23

Evaluation of α-cyanoesters as fluorescent substrates for examining interindividual variation in general and pyrethroid-selective esterases in human liver microsomes

Craig E Wheelock, Åsa M Wheelock, Rong Zhang, Jeanette E Stok, Christophe Morisseau, Susanna E Le Valley, Carol E Green, Bruce D Hammock

Journal:

Analytical Biochemistry

Year:

2003

Language:

english

File:

PDF, 344 KB

english, 2003

24

Asymmetric hydrolysis of racemic para-nitrostyrene oxide using an epoxide hydrolase preparation from Aspergillus niger

Christophe Morisseau, Hariharan Nellaiah, Alain Archelas, Roland Furstoss, Jacques C Baratti

Journal:

Enzyme and Microbial Technology

Year:

1997

Language:

english

File:

PDF, 870 KB

english, 1997

25

Regio- and enantioselective hydrolysis of phenyloxiranes catalyzed by soluble epoxide hydrolase

Kristin C. Williamson, Christophe Morisseau, Joseph E. Maxwell, Bruce D. Hammock

Journal:

Tetrahedron: Asymmetry

Year:

2000

Language:

english

File:

PDF, 545 KB

english, 2000

26

3-D QSAR analysis of inhibition of murine soluble epoxide hydrolase (MsEH) by benzoylureas, arylureas, and their analogues

Yoshiaki Nakagawa, Craig E. Wheelock, Christophe Morisseau, Marvin H. Goodrow, Bruce G. Hammock, Bruce D. Hammock

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 898 KB

english, 2000

27

Gerry Brooks and epoxide hydrolases: four decades to a pharmaceutical

Christophe Morisseau, Bruce D Hammock

Journal:

Pest Management Science

Year:

2008

Language:

english

File:

PDF, 294 KB

english, 2008

28

Development of an online SPE–LC–MS-based assay using endogenous substrate for investigation of soluble epoxide hydrolase (sEH) inhibitors

Nils Helge Schebb, Marion Huby, Christophe Morisseau, Sung Hee Hwang, Bruce D. Hammock

Journal:

Analytical and Bioanalytical Chemistry

Year:

2011

Language:

english

File:

PDF, 313 KB

english, 2011

29

Attenuation of cisplatin nephrotoxicity by inhibition of soluble epoxide hydrolase

Alan R. Parrish, Gang Chen, Robert C. Burghardt, Takaho Watanabe, Christophe Morisseau, Bruce D. Hammock

Journal:

Cell Biology and Toxicology

Year:

2009

Language:

english

File:

PDF, 400 KB

english, 2009

30

Synthesis and SAR of conformationally restricted inhibitors of soluble epoxide hydrolase

Paul D. Jones, Hsing-Ju Tsai, Zung N. Do, Christophe Morisseau, Bruce D. Hammock

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2006

Language:

english

File:

PDF, 194 KB

english, 2006

31

Erratum to “3-D QSAR Analysis of Inhibition of Murine Soluble Epoxide Hydrolase (MsEH) by Benzoylureas, Arylureas, and their Analogues”: [Bioorg. Med. Chem. 8 (2000) 2663]

Yoshiaki Nakagawa, Craig E. Wheelock, Christophe Morisseau, Marvin H. Goodrow, Bruce G. Hammock, Bruce D. Hammock

Journal:

Bioorganic & Medicinal Chemistry

Year:

2001

Language:

english

File:

PDF, 56 KB

english, 2001

32

Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammation

Jun-Yan Liu, Hsing-Ju Tsai, Sung Hee Hwang, Paul D Jones, Christophe Morisseau, Bruce D Hammock

Journal:

British Journal of Pharmacology

Year:

2009

Language:

english

File:

PDF, 310 KB

english, 2009

33

Impact of Epoxyeicosatrienoic Acids in Lung Ischemia–Reperfusion Injury

MARY I. TOWNSLEY, CHRISTOPHE MORISSEAU, BRUCE HAMMOCK, JUDY A. KING

Journal:

Microcirculation

Year:

2010

Language:

english

File:

PDF, 367 KB

english, 2010

34

Expression and Regulation of Soluble Epoxide Hydrolase in Adipose Tissue

Bart M. De Taeye, Christophe Morisseau, Julie Coyle, Joseph W. Covington, Ayala Luria, Jun Yang, Sheila B. Murphy, David B. Friedman, Bruce B. Hammock, Douglas E. Vaughan

Journal:

Year:

2010

Language:

english

File:

PDF, 374 KB

english, 2010

35

Soluble epoxide hydrolase: a novel therapeutic target in stroke

Zhang, Wenri, Koerner, Ines P, Noppens, Ruediger, Grafe, Marjorie, Tsai, Hsing-Ju, Morisseau, Christophe, Luria, Ayala, Hammock, Bruce D, Falck, John R, Alkayed, Nabil J

Journal:

Journal of Cerebral Blood Flow and Metabolism

Year:

2007

Language:

english

File:

PDF, 253 KB

english, 2007

36

Near-Infrared Spectroscopy as a Nondestructive Alternative to Conventional Tablet Hardness Testing

Karen M. Morisseau, Christopher T. Rhodes

Journal:

Pharmaceutical Research

Year:

1997

File:

PDF, 360 KB

1997

37

Prevention of hypertension in DOCA-salt rats by an inhibitor of soluble expoxide hydrolase

David Loch, Andrew Hoey, Christophe Morisseau, Bruce O. Hammock, Lindsay Brown

Journal:

Cell Biochemistry and Biophysics

Year:

2007

Language:

english

File:

PDF, 350 KB

english, 2007

38

Human soluble epoxide hydrolase: Structural basis of inhibition by 4-(3-cyclohexylureido)-carboxylic acids

German A. Gomez, Christophe Morisseau, Bruce D. Hammock, David W. Christianson

Journal:

Protein Science

Year:

2006

Language:

english

File:

PDF, 513 KB

english, 2006

39

Design, Synthesis, and Biological Activity of 1,3-Disubstituted Ureas as Potent Inhibitors of the Soluble Epoxide Hydrolase of Increased Water Solubility

Kim, In-Hae, Morisseau, Christophe, Watanabe, Takaho, Hammock, Bruce D.

Journal:

Journal of Medicinal Chemistry

Year:

2004

Language:

english

File:

PDF, 215 KB

english, 2004

40

The Role of Methyl-Linoleic Acid Epoxide and Diol Metabolites in the Amplified Toxicity of Linoleic Acid and Polychlorinated Biphenyls to Vascular Endothelial Cells

Rabih Slim, Bruce D. Hammock, Michal Toborek, Larry W. Robertson, John W. Newman, Christophe H.P. Morisseau, Bruce A. Watkins, Viswanathan Saraswathi, Bernhard Hennig

Journal:

Toxicology and Applied Pharmacology

Year:

2001

Language:

english

File:

PDF, 219 KB

english, 2001

41

The structure–activity relationship of urea derivatives as anti-tuberculosis agents

Joshua R. Brown, Elton J. North, Julian G. Hurdle, Christophe Morisseau, Jerrod S. Scarborough, Dianqing Sun, Jana Korduláková, Michael S. Scherman, Victoria Jones, Anna Grzegorzewicz, Rebecca M. Crew

Journal:

Bioorganic & Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.13 MB

english, 2011

42

Design, synthesis and evaluation of non-urea inhibitors of soluble epoxide hydrolase

Stevan Pecic, Shi-Xian Deng, Christophe Morisseau, Bruce D. Hammock, Donald W. Landry

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 3.29 MB

english, 2012

43

Pharmacokinetic screening of soluble epoxide hydrolase inhibitors in dogs

Hsing-Ju Tsai, Sung Hee Hwang, Christophe Morisseau, Jun Yang, Paul D. Jones, Takeo Kasagami, In-Hae Kim, Bruce D. Hammock

Journal:

European Journal of Pharmaceutical Sciences

Year:

2010

Language:

english

File:

PDF, 1.20 MB

english, 2010

44

Biocatalysis in ionic liquids: the stereoconvergent hydrolysis of trans-β-methylstyrene oxide catalyzed by soluble epoxide hydrolase

Cinzia Chiappe, Elsa Leandri, Serena Lucchesi, Daniela Pieraccini, Bruce D Hammock, Christophe Morisseau

Journal:

Journal of Molecular Catalysis B: Enzymatic

Year:

2004

Language:

english

File:

PDF, 84 KB

english, 2004

45

Soluble epoxide hydrolase inhibition reveals novel biological functions of epoxyeicosatrienoic acids (EETs)

Bora Inceoglu, Kara R. Schmelzer, Christophe Morisseau, Steve L. Jinks, Bruce D. Hammock

Journal:

Prostaglandins and Other Lipid Mediators

Year:

2007

Language:

english

File:

PDF, 276 KB

english, 2007

46

Multiphoton spectral analysis of benzo[a]pyrene uptake and metabolism in a rat liver cell line

Rola Barhoumi, Youssef Mouneimne, Ernesto Ramos, Christophe Morisseau, Bruce D. Hammock, Stephen Safe, Alan R. Parrish, Robert C. Burghardt

Journal:

Toxicology and Applied Pharmacology

Year:

2011

Language:

english

File:

PDF, 2.19 MB

english, 2011

47

Inhibition of soluble epoxide hydrolase contributes to the anti-inflammatory effect of antimicrobial triclocarban in a murine model

Jun-Yan Liu, Hong Qiu, Christophe Morisseau, Sung Hee Hwang, Hsing-Ju Tsai, Arzu Ulu, Nipavan Chiamvimonvat, Bruce D. Hammock

Journal:

Toxicology and Applied Pharmacology

Year:

2011

Language:

english

File:

PDF, 630 KB

english, 2011

48

Development of monoclonal antibodies to human microsomal epoxide hydrolase and analysis of “preneoplastic antigen”-like molecules

Hongying Duan, Kazunori Yoshimura, Nobuharu Kobayashi, Kazuo Sugiyama, Jun-ichi Sawada, Yoshiro Saito, Christophe Morisseau, Bruce D. Hammock, Toshitaka Akatsuka

Journal:

Toxicology and Applied Pharmacology

Year:

2012

Language:

english

File:

PDF, 946 KB

english, 2012

49

Monoclonal antibodies reveal multiple forms of expression of human microsomal epoxide hydrolase

Hongying Duan, Akira Takagi, Hidekazu Kayano, Isamu Koyama, Christophe Morisseau, Bruce D. Hammock, Toshitaka Akatsuka

Journal:

Toxicology and Applied Pharmacology

Year:

2012

Language:

english

File:

PDF, 795 KB

english, 2012

50

Purification and characterization of a methylene urea-hydrolyzing enzyme from Rhizobium radiobacter (Agrobacterium tumefaciens)

Marja E. Koivunen, Christophe Morisseau, John W. Newman, William R. Horwath, Bruce D. Hammock

Journal:

Soil Biology and Biochemistry

Year:

2003

Language:

english

File:

PDF, 304 KB

english, 2003

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